Proven Non-β-Lactam Antibiotic Allergy in Children

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Proven Non-β-Lactam Antibiotic Allergy in Children.

BACKGROUND Parallel to the increasing use of non-β-lactam (NBL) antibiotics, allergic reactions to this drug group seem to increase. Data about NBL antibiotic hypersensitivity in children are limited. The aim of this study is to evaluate characteristic reactions to NBL antibiotics in children. METHOD Patients with suspected NBL allergy were assessed between 2011 and 2015. Characteristics of t...

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β-lactam allergy: clinical implications and costs

BACKGROUND β-lactam allergy is the most commonly reported medication allergy and it remains a key issue in antibiotic prescribing. A detailed and accurate history taking play a key role in preventing potentially serious clinical incidents and it may contribute in reducing costs. METHODS Data were collected for patients with a documented penicillin allergy on their drug chart during a six mont...

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Occupational allergy to β-lactam antibiotics

Background Contact urticaria in atopic patients was described by Hannuksela [1], among others, in 1980. It generally appears within 30 min of allergen contact and, in the majority of cases, is restricted to the areas of contact; however, local spread and generalized urticaria in the sense of anaphylaxis are seen. Allergic rhinoconjunctivitis and asthma may also subsequently occur [2]. Von Krogh...

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Optimizing empiric antibiotic therapy in patients with severe β-lactam allergy.

Antibiotic selection is challenging in patients with severe β-lactam allergy due to declining reliability of alternate antibiotics. Organisms isolated from these patients may exhibit unique resistance phenotypes. The objective of this study was to determine which alternate antibiotics or combinations provide adequate empirical therapy for patients with β-lactam allergy who develop Gram-negative...

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Allergy to b-Lactam Antibiotics in Children

Background. Skin tests with soluble b-lactams can be used to diagnose immediate and delayed hypersensitivity (HS) reactions to b-lactam antibiotics. Very few studies have been performed with children with suspected b-lactam allergy. In these studies, immediate HS to b-lactams was diagnosed by skin tests in 4.9% to 40% of children. The diagnostic and predictive values of immediate responses in s...

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ژورنال

عنوان ژورنال: International Archives of Allergy and Immunology

سال: 2016

ISSN: 1018-2438,1423-0097

DOI: 10.1159/000443830